Dongwoon Lee (dwlee at cs dot toronto dot edu)  
     
  Numerical Analysis and Scientific Computing Group  
  Computer Science, University of Toronto  
     
     
  Biomechanics and Assistive Technology Laboratory  
  Physical Therapy, University of Toronto  
     


Research Interest  
     
Computational aspects of medical and clinical problems, specifically focusing on modeling, visualization and simulation of human tissues including muscle, ligament, tendon, nerve and skeleton. The purpose of presented studies is to develop computational platforms to reconstruction and quantification of both structural and functional properties of tissues with enhanced reliability and consistency. Both cadaveric and in vivo assessments (e.g., X-ray, Ultrasound, CT) are accounted for. Pathological studies (e.g., tendon rupture, bone deformity and muscle atrophy) are also conducted. These studies are based on the active collaboration with researchers from various disciplines : applied mathematics, graphics, anatomy, biomechanics, kinesiology, orthopedics, radiology and physical therapy.  Other interest includes numerical optimization, finite element method, fluid mechanics, continuum mechanics and graphics.
     

 

  Research Projects  (Current)  
     
  1. Reliable quantification and reconstruction of muscle architecture  (PhD thesis title)  
  Supervisors: Ken Jackson (CS), Eugene Fiume (CS), Anne Agur (Anatomy)  
  2. 3D reconstruction and assessment of spinal deformity (idiopathic scoliosis)  
  Supervisors: Karl Zabjek (PT, BMech), Reinhard Zeller (Surgery, SickKids)  
  3. 3D reconstruction and visualization of stem cell distribution  
  Supervisors: Penny Gilbert (IBBME)  
     
  Publications  
 

 

 
  1. Z. Li, J. Mogk, D. Lee, J. Bibliowicz and A. Agur, Development of an architecturally comprehensive database of forearm flexors and extensors from a single cadaveric specimen, Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 3:1, 2014  
  2. D. Lee, Z. Li, Z. Sohail, K. Jackson, E. Fiume and A. Agur, A three-dimensional approach to pennation angle estimation for human skeletal muscle, Computer Methods in Biomechanics and Biomedical Engineering, 18:13, May 2014  
  3. Z. Li, J. Mogk, D. Lee, J. Bibliowicz and A. Agur, Development of an architecturally comprehensive database of forearm flexors and extensors from a single cadaveric specimen, 1st International Workshop on Biomechanical and Parametric Modeling of Human Anatomy, January 2013  
  4. T. Arakawa, Z. Li, R. Bobotsis, D. Lee, A. Agur, Three-dimensional architecture of the plantar intrinsic muscles of the foot, Clinical Anatomy 25:7, October 2012  
  5. Z. Li, K. Ravichndiran, D. Lee, N. Mckee, A. Agur, An architecturally comprehensive 3D computer model of the intrinsic musculotendinous structures of the hand, Clinical Anatomy 25:7, October 2012  
  6. Z. Sohail, K. Sauks, K. Ravichndiran, J. Laprade, D. Lee, A. Agur, A 3D model of vastus medialis oblique fiber bundle architecture, Clinical Anatomy 25:7, October 2012  
  7. D. Lee, K. Ravichandiran, K. Jackson, E. Fiume and A. Agur, Robust estimation of physiological cross-sectional area and geometric reconstruction of human skeletal muscle, Journal of Biomechanics, 45:8, May 2012  
  8. D. Lee, M. Glueck, A. Khan, E. Fiume and K. Jackson, Modeling and Simulation of Skeletal Muscle: A Survey, Foundations and Trends in Computer Graphics and Vision, April 2012  
  9. D. Lee, Physics-Based Simulation for Fluid Mixtures, Research Paper, March 2007  
     
     
 
Presentations
     
  1. D. Lee, R. Zeller, H. Carnahan, S. Mathur, A. Agur, D. Wang and K. Zabjek, Simulation of vertebral deformity: development of a novel application for pediatric spine surgery, SpineFEST, June 2013  
  2. D. Lee, R. Zeller, H. Carnahan, S. Mathur, A. Agur, D. Wang and K. Zabjek, Simulation of vertebral deformity: development of a novel application for pediatric spine surgery, 5th International Pediatric Simulation Symposia and Workshops (IPSSW), April 2013  
  3. D. Lee, R. Zeller, A. Agur, S. Mathur and K. Zabjek, Development of a three dimensional musculoskeletal modeling application for the study of paediatric spinal deformities, Ontario Biomechanics Conference (OBC), March 2013  
  4. D. Lee, R. Zeller, S. Mathur, K. Zabjek, E Biddiss, A. Agur, H. Carnahan, Development of a Geometric Modeling Application for Spine Research and Education, University of Toronto Spine Program Research Meeting, August 2012  
  5. D. Lee, K. Ravichandiran, K. Jackson, E. Fiume and A. Agur, Robust estimation of physiological cross-sectional area and geometric reconstruction for human skeletal muscle, 30th Southern Ontario Numerical Analysis Day (SONAD), May 2012  
  6. D. Lee, K. Jackson, E. Fiume and A. Agur, Geometric reconstruction and physical simulation of human skeletal muscle, International Conference on Scientific Computation And Differential Equations (SciCADE), July 2011  
 
 
  Softwares  
     
    MuscleModeler    
    Objective: quantification and 3D reconstruction of muscle architecture    
    Development: C++, OpenGL, MFC, Blas, Lapack and Taucs on MS Windows    
         
             
    SpineModeler - G (global and structural deformity)    
    Objective: reconstruction and assessment of structural deformity of spine    
    Development: C++, OpenGL and MFC on MS Windows    
         
             
    SpineModeler - L (local and vertebral deformity)    
    Objective: geometric reconstruction and simulation of vertebral deformity    
    Development: C++, OpenGL, MFC, Blas, Lapack and Taucs on MS Windows    
         
             
    SpineCurve Analyzer    
    Objective: quantification of spinal curves in lateral flexion    
    Development: C++, OpenGL and MFC on MS Windows    
         
             
        CT-based Spine Modeler      
    Objective: 3D reconstruction of spine from CT images     
    Development: C++, OpenGL and MFC on MS Windows     
         
             
MusclePower Analyzer
    Objective: analysis of muscle performance (torque)    
  Development: Matlab on MS Windows
         
             
    FEM-based solid deformer (linear and co-rotational)    
    Objective: physical simulation of deformable solid (linear elasticity)    
    Development: C++, OpenGL, MFC, Blas, Lapack and Taucs on MS Windows    
         
             
    SPH-based fluid solver    
    Objective: physical simulation of inviscid flow (Lagrangian approach)    
    Development: C++, OpenGL, MFC and PBRT on MS Windows    
         
             
    Estimation of Principal Curves    
    Objective: a statistical approach to fit smooth curves into unorganized data    
    Development: C++, Win32 and OpenGL on MS Windows    
         
             
    3D line art rendering    
    Objective: an implementation of  the technical paper, 'SIGGRAPH2001 illustrative smooth surface' (course project)    
    Development: C++, OpenGL and MFC on MS Windows    
         
             
    Single image relighting    
    Objective: synthesizing lighting conditions based on shape from shading (SFS) and intrinsic methods    
Development: Matlab on MS Windows
         
             
             
  Technical paper reviewer    
       
  SIGGRAPH (2014)    
  Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization (2013, 2014)    
  International Journal of Computer Assisted Radiology and Surgery (2015)    
  Journal of Theoretical Biology (2015)